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. 2009 Sep 8;13(5):R144. doi: 10.1186/cc8038

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Copyright ©2009 Zausig et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Comparative effects of etomidate, s(+)-ketamine, midazolam, propofol, and methohexitone on heart rate in rat isolated septic hearts. All drugs except etomidate decreased chronotropic effects. For control values, only the first (CTRL) and the washout (WASH) periods are displayed. After the washout period, the heart rate returned to baseline level. *P < 0.05 midazolam (10^-5to 10^-4M) and propofol (10^-4M) versus control; ^#P < 0.05 midazolam versus etomidate, s(+)-ketamine, propofol, and methohexitone. Data are the means ± standard error of the mean.