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. 2009 Sep 8;13(5):R144. doi: 10.1186/cc8038

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Copyright ©2009 Zausig et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Comparative effects of etomidate, s(+)-ketamine, midazolam, propofol, and methohexitone on left ventricular relaxation in rat isolated septic hearts. All drugs except for s(+)-ketamine decreased lusitropy. For control values, only the first (CTRL) and the washout (WASH) periods are displayed. After the washout period left ventricular relaxation (-dLVP/dt^-1) returned to baseline level. *P < 0.05 midazolam, propofol, and methohexitone vs. control; ^#P < 0.05 midazolam, propofol, and methohexitone vs. etomidate and s(+)-ketamine; ^$P < 0.05 propofol vs. midazolam and methohexitone. Data are the means ± standard error of the mean.