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Receiver operation characteristic analysis using TIMP-1, lactic acid, and SOFA score as predictors of mortality. The areas under the curves (AUC) for each predictor of mortality were the following: tissue inhibitor of matrix metalloproteinase (TIMP)-1 (AUC = 0.68; 95% CI = 0.59 to 0.76; P < 0.001), lactic acid (AUC = 0.67; 95% CI = 0.58 to 0.75; P < 0.001) and Sepsis-related Organ Failure Assessment score (SOFA) score (AUC = 0.71; 95% CI = 0.64 to 0.79; P < 0.001).
