Table 5.

Correlation between MMP-9, MMP-10, and TIMP-1 with TNF-α and IL-10 serum levels

	TNF-α (pg/ml)	IL-10 (pg/ml)	TNF-α/IL-10 ratio
MMP-9: ng/ml	rho = -0.25	rho = -0.38	rho = 0.33
	p = 0.001	p < 0.001	p < 0.001
TIMP-1: ng/ml	rho = 0.56	rho = 0.50	rho = -0.26
	p < 0.001	p < 0.001	p = 0.001
MMP-10: pg/ml	rho = 0.35	rho = 0.30	rho = -0.16
	p < 0.001	p < 0.001	p = 0.04

SOFA = Sepsis-related Organ Failure Assessment score; aPTT = Activated partial thromboplastin time; INR = International normalized ratio; MMP = Matrix metalloproteinase; TIMP = Iissue inhibitor of matrix metalloproteinase; IL = interleukin; rho = Spearman's rank correlation coefficient.