Table 3.
Course of serum creatinine over time in patients after cardiac arrest
| Study population (n = 171) |
CPC 1 + 2 (n = 69) |
CPC 3 + 4 + 5 (n = 102) |
P value | |
|---|---|---|---|---|
| serum creatinine (mg/dl) | ||||
| at admission | 1.24 (1.01-1.65) | 1.20 (0.94-1.49) | 1.32 (1.08-1.68) | 0.039 |
| after 24 hours | 1.12 (0.74-1.87) | 0.79 (0.60-1.49) | 1.35 (0.96-2.06) | < 0.0001 |
| after 72 hours | 1.18 (0.79-2.23) | 0.93 (0.67-1.50) | 1.37 (0.92-2.51) | 0.0174 |
| at ICU discharge | 0.86 (0.68-1.60) | 0.78 (0.64-0.96) | 1.05 (0.72-2.24) | 0.0003 |
| ΔCrea24 | -0.12 (-0.35-0.30) | -0.25 (-0.51-0.02) | 0.02 (-0.23-0.52) | < 0.0001 |
| ΔCrea72 | -0.01 (-0.33-0.68) | -0.13 (-0.38-0.24) | 0.04 (-0.30-0.96) | 0.026 |
Data are presented as medians (25th and 75th percentiles). The differences between patients with CPC 1 to 2 vs. CPC 3 to 5 were significant at every point of assessment. ΔCrea24: change in serum creatinine in the first 24 hours; ΔCrea72: change in serum creatinine in the first 72 hours; CPC: Cerebral Performance Category; ICU = intensive care unit.