Table 1.
PRIS n = 11 |
No PRIS n = 1006 |
P value | |
---|---|---|---|
Age (years)A | 58 ± 14 | 56 ± 18 | 0.64 |
Male (%) | 82 | 65 | 0.4 |
APACHE II scoreA | 25 ± 6 | 20 ± 6 | 0.03 |
Admitting service (%) | |||
Medicine | 36 | 35 | 0.82 |
Surgery | |||
Neurosurgery | 9 | 25 | 0.39 |
Trauma | 9 | 23 | 0.47 |
Other surgery | 46 | 17 | 0.04 |
Primary reason for ICU admit (%) | |||
Trauma | 18 | 23 | 1.0 |
Surgery | 28 | 21 | 0.89 |
Neurological | 9 | 20 | 0.6 |
Respiratory failure | 36 | 17 | 0.2 |
Cardiac | 0 | 9 | 0.61 |
Other | 9 | 10 | 0.77 |
Past medical history (%) | |||
Coronary artery disease | 27 | 30 | 0.89 |
Malignancy | 36 | 18 | 0.24 |
Congestive heart failure | 18 | 18 | 0.71 |
Diabetes | 18 | 16 | 0.83 |
Chronic obstructive pulmonary disease | 27 | 10 | 0.12 |
Other | 9 | 12 | 0.87 |
Use of propofol dose >83 μg/kg/min (%) | 18 | 10 | 0.68 |
Duration of propofol (days)B | 5 (3-7) | 4 (3-7) | 0.43 |
Number of PRIS clinical manifestationsC | 5 (2-7) | 1 (0-6) | 0.0001 |
Duration of ICU stay (days)B | 14 (10-18) | 12 (7-20) | 0.4 |
ICU mortality (%) | 18 | 20 | 0.82 |
Hospital mortality (%) | 18 | 21 | 0.88 |
APACHE = acute physiology and chronic health evaluation; ICU = intensive care unit; PRIS = propofol-relation infusion syndrome.
AMean ± standard deviation
BMedian (interquartile range)
CMedian (Range)