Figure 2.
Effects of PI3 rs2664581 polymorphism on plasma PI3 level. The acute respiratoyr distress syndrome (ARDS) samples were collected within 48 hours of ARDS diagnosis, and the control samples were collected within 48 hours of ICU admission. Geometric mean of plasma PI3 is shown in columns with error bar representing 95% confidence interval. Since the natural log transformed data were used in the analyses, antilogs of the means and 95% confidence intervals are presented in the figure. The subgroup of the ARDS with AA genotype (n = 35) had significant lower plasma PI3 than the ARDS with AC/CC genotypes (n = 19, P = 0.043) and the control with AA genotype (n = 38, P = 0.121) in GLM analyses. P values after adjustment for age, sex, type of lung injury, pre-admission steroid use, septic shock, and APACHE III score. Dark shaded bars, ARDS; light shaded bars, control.