TABLE 5.

BASELINE VALUES RECORDED DURING 5 MINUTES OF EUPNEIC BREATHING BEFORE THE INITIAL INTERVENTION (HYPOXIA OR HYPERCAPNIA) AT THE PRE–CONTINUOUS POSITIVE AIRWAY PRESSURE VISIT AND 6 AND 12 WEEKS AFTER INITIATION OF TREATMENT IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

	Pre-CPAP	6 wk of CPAP	12 wk of CPAP	P Value (ANOVA)
MAP, mm Hg	89 ± 9	87 ± 8	87 ± 11	0.78
HR, bpm	76 ± 10	80 ± 14	77 ± 13	0.34
CFV, cm/s	54.6 ± 10.5	58.7 ± 11.0	60.9 ± 12.0	0.11
FBF, ml/100 ml/min	6.6 ± 3.9	6.7 ± 3.4	6.9 ± 2.8	0.87
e, L/min	8.4 ± 2.4	8.9 ± 2.4	9.2 ± 1.7	0.20
PetCO2, mm Hg	40.9 ± 3.9	41.3 ± 3.6	42.0 ± 3.0	0.12

Definition of abbreviations: ANOVA = analysis of variance; bpm = beats per minute; CFV = cerebral flow velocity; CPAP = continuous positive airway pressure; FBF = forearm blood flow; HR = heart rate; MAP = mean arterial pressure, Pet_CO2 = end-tidal carbon dioxide tension; e = ventilation.

Patients with obstructive sleep apnea: n = 14.

There were no significant differences in any of these baseline variables over time.