Table 1.
Patient characteristics.
| Wound healing experimental group | Chorio (n = 7) |
No chorio (n = 30) |
Steroids (n = 35) |
No steroids (n = 10) |
|---|---|---|---|---|
| Gestational age (weeks) (median (IQR)) | 26.9 (25.6-28.7) | 28.6 (27.0-39.3) | 28.6 (26.9-29.4) | 27.5 (26.2-29.7) |
| Birth weight (grams) (mean ± SD) | 1027 ± 246 | 1069 ± 221 | 1091 ± 223 | 1028 ± 268 |
| BALF total protein day 0/1 (mg/ml) (mean ± SD) | 0.75 ± 0.49 (n = 7) |
0.76 ± 0.47 (n = 28) |
0.82 ± 0.57 (n = 32) |
0.62 ± 0.46 (n = 9) |
| BALF total protein day 3/4 (mg/ml) (mean ± SD) | 1.47 ± 2.38 (n = 5) |
1.25 ± 1.34 (n = 14) |
1.09 ± 1.22 (n = 19) |
3.21 ± 3.53 (n = 2) |
| BALF total protein day 7 (mg/ml) (mean ± SD) | 0.84 ± 0.39* (n = 3) |
0.44 ± 0.18 (n = 7) |
0.51 ± 0.28 (n = 9) |
0.95 ± 0.03 (n = 2) |
| Total population |
Chorio (n = 8) |
No chorio (n = 37) |
Steroids (n = 51) |
No steroids (n = 11) |
| Gestational age (weeks) (median (IQR)) | 26.5 (25.7-28.4) | 28.4 (26.8-29.4) | 28.6 (26.9-29.4) | 27.6 (26.3-29.7) |
| Birth weight (grams) (mean ± SD) |
1014 ± 231 | 1045 ± 228 | 1079 ± 236 | 1045 ± 260 |
General characteristics of different patient groups included in the cell culture experiments and the total population (including VEGF and KGF quantification).
*p < 0.05 vs no chorioamnionitis day 7.
Abbreviations: chorio = chorioamnionitis; IQR = interquartile range; SD = standard deviation.