Table 3.
A. Clinical context and clinical manifestations | 1. History of biliary disease |
2. Fever and/or chills | |
3. Jaundice | |
4. Abdominal pain (RUQ or upper abdominal) | |
B. Laboratory data | 5. Evidence of inflammatory responsea |
6. Abnormal liver function testsb | |
C. Imaging findings | 7. Biliary dilatation, or evidence of an etiology (stricture, stone, stent etc) |
Suspected diagnosis | Two or more items in A |
Definite diagnosis | (1) Charcot’s triad (2 + 3 + 4) |
(2) Two or more items in A + both items in B and item C |
a Abnormal WBC count, increase of serum CRP level, and other changes indicating inflammation
b Increased serum ALP, r-GTP (GGT), AST, and ALT levels