. 2007 Jan 30;14(1):78–82. doi: 10.1007/s00534-006-1159-4

Table 5.

Criteria for severe (grade III) acute cholecystitis

“Severe” acute cholecystitis is accompanied by dysfunctions in any one of the following organs/systems

1. Cardiovascular dysfunction (hypotension requiring treatment with dopamine ≧5 µg/kg per min, or any dose of dobutamine)

2. Neurological dysfunction (decreased level of consciousness)

3. Respiratory dysfunction (PaO₂/FiO₂ ratio <300)

4. Renal dysfunction (oliguria, creatinine >2.0 mg/dl)

5. Hepatic dysfunction (PT-INR >1.5)

6. Hematological dysfunction (platelet count <100 000/mm³)