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. Author manuscript; available in PMC: 2009 Nov 27.
Published in final edited form as: Bioorg Med Chem. 2008 Oct 17;16(24):10345–10355. doi: 10.1016/j.bmc.2008.10.030

Table 1.

Activity of inhibitors of the cytochrome bc1 complex

Compound Inhibitor Wheat Powdery
Mildew
Wheat Glume
Blotch
Potato Late
Blight
Vine Downy
Mildew
Wheat Brown
Rust
NADH oxidaseIC50
(nM)
Breakpointa (μM)
8 Crocacin A >180b >180 >180 45 45 56
11 Crocacin D >180 45 45 45–9 9 36
2 Stigmatellin >180 >180 >180 180 >180 81
7 Azoxystrobin <1.8c <1.8 <1.8 <1.8 <1.8 120
a

breakpoint is the lowest concentration at which control of disease was 100%

b

> indicates that the compound was not active at the highest concentration tested.

c

< indicates that the compound was 100% active at this concentration but was not tested at lower concertrations.