ASPS Xenograft Histology and Nuclear Reactivity to ASPL-TFE3 type 1 and ASPL-TFE3 type 2 Antibodies.
ASPS xenograft tumors, maintained in female NOD.SCID\NCr mice, were harvested at the indicated passage (see timeline illustrated in Figure 1), fixed in 10% buffered formalin and embedded in paraffin. Sections (4μm) were stained with Periodic Acid Schiff (PAS)( Panel A) or with affinity-purified polyclonal antibodies to either the ASPLTFE3 type 1 fusion protein (Panel B) or to the ASPL-TFE3 type 2 fusion protein (Panel C). (See reference 3 for details of staining).