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. Author manuscript; available in PMC: 2010 Nov 15.
Published in final edited form as: J Immunol. 2009 Oct 19;183(10):6346–6358. doi: 10.4049/jimmunol.0901773

Figure 5.

Figure 5

Post-transplant CD8 Treg cells mediate contact-independent suppressive activity, whereas pre-transplant CD8 T cells show contact-dependent helper function. Pre-transplant or post-transplant CD8 cells were cocultured with autologous IL-2 stimulated CD4 line T cells in contact or separated by transwell membrane by the ratio of 1 : 0.5 (target T cells : CD8 T cells). Culture conditions were similar to that in Figure 3, results from five experiments are shown, and the bars represent the mean ± SD. * p < 0.01.