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Immunohistochemical analysis of PPP2CA expression on a prostate cancer tissue array. A and B, Normal/benign tissue at 10X and 40 × magnifications, respectively. C, Prostate cancer section with various grade lesions (10× magnification), D and E, magnified (40X) view of section depicting lesions with Gleason grade 6 (3+3) and 8 (4+4), respectively. A decreased expression of PPP2CA is observed in prostate cancer, which further correlates with Gleason grade.
