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. Author manuscript; available in PMC: 2009 Nov 29.
Published in final edited form as: Neurobiol Dis. 2009 Feb 26;34(3):417–431. doi: 10.1016/j.nbd.2009.02.009

Fig. 4.

Fig. 4

(a) TfR2 is colocalized with tyrosine hydroxylase (TH) in dopamine neurons of the substantia nigra, as assessed by laser scanning confocal microscopy. (b) Dopaminergic neurons of the substantia nigra pars compacta (SNc) stain intensely for TfR2, while neurons in the adjacent substantia nigra pars reticulata (SNr) contain little, if any, TfR2. Note the clear cytoplasm (arrows) surrounding neuronal nuclei in SNr, which is in marked contrast to the pattern in SNc. There is also substantial TfR2 immunoreactivity in the neuropil of SNr.