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. Author manuscript; available in PMC: 2009 Nov 30.
Published in final edited form as: Biometrics. 2008 Mar 19;64(4):1032–1042. doi: 10.1111/j.1541-0420.2008.01011.x

Table 4.

Results from simulation study under setting 2

Type of parameterb True
value
Mean
estimate
Sample
SEa
Mean
Asy. SEa
Mean
bootstrap SE
β12 Age 0.036 0.037 0.0060 0.0016 0.0062
Tran 0.16 0.15 0.042 0.035 0.039
Frail 0.90 0.87 0.190 0.120 0.190
Frail:tran −0.084 −0.081 0.039 0.020 0.040
Alone −0.26 −0.28 0.096 0.074 0.099
Alone:tran 0.037 0.038 0.031 0.024 0.030
Depress 0.28 0.25 0.094 0.053 0.095
β13 Age 0.075 0.075 0.020 0.003 0.019
β21 Age −0.015 −0.015 0.0054 0.003 0.0056
Tran −0.012 −0.015 0.012 0.019 0.017
Frail −0.26 −0.27 0.17 0.14 0.17
β23 Frail −0.81 −0.82 0.27 0.26 0.27
Tran −0.13 −0.12 0.066 0.066 0.069
Frail:tran 0.12 0.13 0.057 0.057 0.062
Sex −0.81 −0.81 0.18 0.19 0.19
γ12 1 1 0 0 0
γ13 −0.5 −0.66 1.30 1.07 1.32
γ21 1 1 0 0 0
γ23 5.0 5.36 1.79 1.44 1.82
Variance var(ηi1) 0.16 0.13 0.050 0.052 0.049
Components cov(ηi1, ηi2) −0.05 0.036 0.013 0.016 0.012
var(ηi2) 0.02 0.015 0.006 0.008 0.006
a

The “Sample SE” denotes the standard deviation of the parameter estimates from 100 simulated data sets and the “Mean Asy. SE” denotes the average of the asymptotic standard errors obtained from the 100 simulated data sets.

b

We use k to index the state from which transition is made. We use l = 2 and 3 to denote the states of disability and death that can be transited to from state 1. We use l = 1 and 3 to denote the states of independence and death that can be transited to from state 2.