Figure 3.
Correlation between the unidirectional uptake rate (K) derived from the reduced compartmental model (k4 = 0) and either the k3 parameter (A) or the standard uptake value (SUV) for AMT (B). Tumors obtained from different patients are marked by different symbols. The k3 parameter was highly correlated with K indicating that metabolic conversion is the dominant factor in AMT tracer uptake in tumors. Moreover, the K was also significantly correlated with the SUV for AMT suggesting that this semi-quantitative value can provide an estimate of the magnitude of metabolic conversion.