Table 1.
Baseline Clinical Characteristics
| Variable | PCI (n=195) | MED (n=186) |
|---|---|---|
| Mean age (range), y | 57.3 (34–80) | 57.8 (33–81) |
| Female, n (%) | 33 (16.9) | 33 (17.7) |
| Race, n (%) | ||
| White | 160 (82.1) | 151 (81.2) |
| Black | 6 (3.1) | 5 (2.7) |
| Other | 29 (14.9) | 30 (16.1) |
| No. (%) with history of: | ||
| Diabetes* | 32 (16.4) | 47 (25.3) |
| Hypertension | 89 (45.6) | 92 (49.5) |
| Hyperlipidemia | 108 (55.4) | 111 (59.7) |
| Prior MI | 25 (12.8) | 17 (9.1) |
| Cerebrovascular disease† | 11 (5.6) | 1 (0.5) |
| PVD | 5 (2.6) | 3 (1.6) |
| CHF | 4 (2.1) | 3 (1.6) |
| Prior PCI | 8 (4.1) | 4 (2.2) |
| Current smoker, n (%) | 66 (33.8) | 65 (34.9) |
| NYHA class at randomization, n (%) | ||
| Class I | 182 (93.3) | 170 (91.4) |
| Class II | 13 (6.7) | 16 (8.6) |
| Class III or IV | 0 | 0 |
| Body mass index,† mean±SD | 27.5±4.2 (n=195) | 28.8±5.1 (n=186) |
| Heart rate, bpm, mean±SD | 69.2±12.2 (n=195) | 69.8±12.4 (n=186) |
| Systolic blood pressure, mm Hg, mean±SD | 116.6±16.0 (n=195) | 117.1±17.0 (n=186) |
| Diastolic blood pressure, mm Hg, mean±SD | 71.0±11.2 (n=195) | 70.8±12.1 (n=186) |
| Serum creatinine, mg/dL, mean±SD | 1.0±0.2 (n=191) | 1.0±0.2 (n=184) |
| Creatinine clearance, mL/min, mean±SD | 83.1±19.8 (n=191) | 82.3±21.4 (n=184) |
PVD indicates peripheral vascular disease; CHF, congestive heart failure.
*
P=0.03,
†
P=0.01.