Table 1.
The exact mutations and their frequencies in gastric cancer tissues
| p53 | n | n | n | KRAS | n | BRAF | PIK3CA | n | ||
| 44% (40/90) | 6% (5/90) | 0% (0/90) | 4% (4/90) | |||||||
| G524A (R175H) | 3 | G469T (V157F) | 2 | G733A (G245S) | 2 | G35A (G12D) | 3 | A3140G (H1047R) | 3 | |
| C742T (R248W) | 2 | G743A (R248Q) | 2 | C817T (R273C) | 2 | G35T (G12V) | 2 | G1624A (E542K) | 1 | |
| G818A (R273H) | 2 | C844T (R282W) | 2 | C200G (P67R) | 1 | |||||
| G313T (G105C) | 1 | G422A (C141Y) | 1 | G461T (G154V) | 1 | |||||
| G473A (R158H) | 1 | C489G (Y163X) | 1 | G524T (R175L) | 1 | |||||
| C574T (Q192X) | 1 | A578G (H193R) | 1 | G586T (R196X) | 1 | |||||
| G587C (R196P) | 1 | A614G (Y205C) | 1 | C637T (R213X) | 1 | |||||
| G638A (R213Q) | 1 | G646A (V216M) | 1 | A659G (Y220C) | 1 | |||||
| G725T (C242F) | 1 | G731T (G244V) | 1 | G733T (G245V) | 1 | |||||
| C742G (R248G) | 1 | C817A (R273S) | 1 | T823G (C275G) | 1 | |||||
| C847T (R283C) | 1 |
Nucleotide substitution (amino acid change) is shown.