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. Author manuscript; available in PMC: 2009 Nov 30.
Published in final edited form as: Basic Res Cardiol. 2007 Jul 27;102(5):369–392. doi: 10.1007/s00395-007-0666-z

Fig. 13.

Fig. 13

Hypothetical vicious cycle (and potential targets for therapeutic interventions) of defects in EC coupling and energy depletion in chronic heart failure. PCr phosphocreatine; PLB phospholamban; SERCA SR Ca2+-ATPase