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Effect of 4-HNE on the extent of lipid peroxidation in control (triangles) and hGSTA4-transfected cells (squares). Cells were incubated in the presence of 0–20 μM 4-HNE (or 0.05% ethanol control) and assayed at 2 hr for the extent of lipid peroxidation. Data represents mean ± SEM of three replicate experiments and asterisks indicate significant differences in lipid peroxidation among control and hGSTA4 cells using one-way ANOVA at p≤0.05.
