FIGURE 1.

Comparative genomic analysis during zebrafish regeneration. A, heat map illustrating the changes in gene expression during the progression of larval fin regeneration. Non-amputated fin tissue at 2 dpf (0 dpa) was used as the control to compare with the regenerating fin at 1, 2, and 3 dpa. B, the genes that were at least 2-fold differentially expressed were grouped based on the known function of the proteins. Comparative gene expression profiling was performed between larval fin, adult fin, and adult heart regeneration systems in zebrafish. The Venn diagram comparing the genes that were modulated during regeneration between C, larval and adult fin regeneration; D, larval fin and adult heart regeneration; and E, larval fin, adult fin, and adult heart regeneration models.