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. 2009 Nov 16;106(47):19940–19945. doi: 10.1073/pnas.0907898106

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Fig. 1. — Ad-induced T-cell expansion correlates with Ad5 serostatus. (A) CFSE-labeled lymphocytes from 20 individuals were co-cultured for 5 days with Ad5, Ad11, tetanus toxoid, influenza, or SEB-stimulated DCs. The mean percentages ± SD of proliferating (CFSE low) CD4 (triangles) and CD8 (squares) T cells are shown. (B) The percentages of proliferating CD4 T cells in response to Ad5 stimulation (x axis) were plotted against those in response to Ad11-pulsed DCs (y axis). P and R values were obtained using the spearman correlation test. (C) The percentages of expanded Ad5, Ad11, tetanus toxoid, influenza, and SEB-specific CD4 T cells (y axis) were plotted against the individuals' Ad5 antibody titers (x axis). Continued and dotted lines represent the best fit line and 95% confidence intervals respectively, whilst R and P values were obtained using the Spearman test.