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A common virus-binding hotspot on ACE2 for the binding of both NL63-CoV and SARS-CoV. (A) Stick-and-ball representation of the hotspot at the NL63-CoV–ACE2 interface. (B) Corey-Pauling-Koltun representation of the hotspot at the NL63-CoV–ACE2 interface. (C) Stick-and-ball representation of the hotspot at the SARS-CoV–ACE2 interface. (D) Corey-Pauling-Koltun representation of the hotspot at the SARS-CoV–ACE2 interface.
