TABLE 2.
Comparison (Wilcoxon) of HAS isoform transcript levels and HA in the culture medium in preadipocytes (n = 10) from various fat depots (predominantly subcutaneous), either control or expressing activating mutant TSHR (L629F)
HAS1 and HAS2 TCN are expressed per 1000 copies of the housekeeping gene. HA is expressed as ng/104 cells. The results are the means ± S.E. of all samples analyzed in the group, with each individual sample being measured in triplicate.
| Control | L629F | p value | |
|---|---|---|---|
| HAS1 TCN | 21.2 ± 7.5 | 57.7 ± 22.9 | p < 0.02 |
| HAS2 TCN | 226 ± 84.2 | 356 ± 134 | p < 0.04 |
| HA ng/104 cells | 657 ± 174 | 931 ± 135 | p < 0.03 |