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. 2009 Jul 28;284(39):26655–26665. doi: 10.1074/jbc.M109.021956

TABLE 1.

paGFPu rates of degradation

p values were determined by two-tailed unpaired Student's t test.

Conditions Rate of degradation p value No. imaged dendrites
% Fluorescence decay/2 min
Controla 2.43 ± 0.50 21
MG132 0.58 ± 0.39 0.009 16
Vinyl sulfone 0.55 ± 0.29 0.025 9
Epoxomicin 0.87 ± 0.18 0.035 11
Calcium-free 0.67 ± 0.19 0.012 13
APV 1.34 ± 0.27 0.115 13
Nimodipine 1.70 ± 0.05 0.418 7
CNQX 2.14 ± 0.28 0.704 10
BIC, t 10 min 5.67 ± 0.51 <0.001 27
BIC, t 20 min 4.06 ± 0.37 0.01 27
BIC, t 60 min 1.65 ± 0.07 0.47 5
AMPA 5.90 ± 0.34 <0.001 11
TTX 1.13 ± 0.10 0.02 19
KN-93 1.39 ± 0.12 0.076 16
paGFPb 0.25 ± 0.25 0.003 13
BICa 4.06 ± 0.37 27
MG132 + BIC 1.54 ± 0.31 0.001 8
Calpeptin + BIC 3.92 ± 0.40 0.814 15
paGFPb + BIC 1.27 ± 0.12 <0.001 12
APV + BIC 1.90 ± 0.26 <0.001 14
Nimodipine + BIC 1.67 ± 0.30 0.001 10
CNQX + BIC 1.25 ± 0.16 0.003 5
KN-93 + BIC 1.58 ± 0.11 <0.001 17

a Indicates reference category.

b paGFP, no-degron control reporter.