. Author manuscript; available in PMC: 2009 Nov 30.

Published in final edited form as: Am J Ophthalmol. 2008 Sep 5;146(5):649–655.e6. doi: 10.1016/j.ajo.2008.07.013

Table 1.

Diffuse Edema

Clinical Examination or Fundus Photography
Reference	Center of the Macula Thickened?	Lipid Exudates	Pattern of Lipid	Area	Vitreomacular Traction
Blankenship, 1979
Bresnick, 1983	implied	absence^* or paucity	NPD	extensive^* areas	NPD
Bresnick, 1986	implied	usually^* absent	NPD	NPD	NPD
ETDRS, 1995
Akduman, 1999; Akduman 1997	NPD	NPD	NPD	≥2DAs	NPD
Lovestam-Adrian, 2000	within 1 DD of center	none within 1 DD of center	NPD	≥1 DD	NPD
Martidis, 2002	implied	scarcity^*	NPD	extensive^* areas	NPD
Funatsu, 2003
Audren, 2004	yes	few^*	NPD	NPD	no
Ciardella, 2004	yes	NPD	NPD	entire macula	NPD
Kang, 2004	NPD	NPD	NPD	≥ 1DA	NPD
Laursen, 2004	yes	NPD	NPD	≥2 DAs	NPD
Massin, 2004	yes	few^*	NPD	NPD	no
Bonini-Filho, 2005	yes	NPD	NPD	NPD	NPD
Catier, 2005	yes	few^* or no exudates	NPD	NPD	NPD
Cardillo, 2005	yes	few^*	NPD	NPD	NPD
Luttrull, 2005	yes	NPD	NPD	involves all 4 quadrants of macula	NPD
Tunc, 2005	NPD	NPD	NPD	NPD	NPD
Audren, 2006	yes	few^*	NPD	NPD	NPD
Jensen, 2006	NPD	NPD	NPD	nearly the entire macula^*	NPD
Kang, 2006	within 1 DD of center	NPD	NPD	≥ 1 DA	NPD
Kim, 2006
Zein, 2006	yes	NPD	NPD	all 4 quadrants of macula involved	NPD
Brasil, 2007	yes	NPD	NPD	NPD	NPD
Carpineto, 2007	yes	NPD	NPD	entire macula^*	NPD
Shimura, 2007;Shimura, 2004	NPD	NPD	NPD	≥2DAs	NPD
Kang, 2008	yes	NPD	NPD	NPD	no

DD=disk diameter, DA= disk area, NPD=not part of definition, either=yes or no, mas=microaneurysms, FAZ= foveal avascular zone, GS=graded separately,

=undefined term. Blank cells indicate that the modality is not used in the definition in the reference of the row in question. This table is not represented to reflect an exhaustive review of the literature.