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Figure 3. Representation of the 7 apoptosis-related genes differentially expressed upon CD31/CD38 engagement.

Figure 3

Expression pattern of 7 genes of the 1,645 gene signature that are also part of the 30 apoptosis-regulating genes reported in (14). Red squares refer to up-regulation in the sample with respect to the Universal Reference, while green squares to down-regulation. Expression ratios are represented in a log10 scale. All the genes but Mcl-1 increase their expression as a consequence of CD31/CD38 interactions. Two different Agilent probes specific for Bax are over-expressed in the L-CD31+ condition.