Table 1.
Clinical and biological features of the CLL patients
| Patient No. | Age (yr) | Sex | Stage | YD | TX | IgVH (%)* | CD38 (%) | ZAP-70 (%) | FISH |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 60 | F | 0/A | 10 | T | 100 | 54 | 2 | 11q- |
| 2 | 65 | F | 2/A | 7 | T | 100 | 35 | 12 | 11q-,13q- |
| 3 | 72 | F | 0/A | 7 | NT | - | 70 | 11 | +12,17p- |
| 4 | 47 | M | 2/A | 21 | T | 91.2 | 75 | 0 | ND |
| 5 | 57 | M | 4/C | 7 | T | 97 | 79 | 9 | ND |
| 6 | 83 | M | 2/A | 5 | T | 99.7 | 66 | 23 | +12 |
| 7 | 75 | F | 1/B | 6 | NT | 99 | 42 | 12 | 17p- |
| 8 | 61 | M | 4/A | 8 | NT | 99.3 | 78 | 21 | ND |
| 9 | 48 | M | 2/B | 8 | T | 99.1 | 34 | 35 | 13q- |
| 10 | 67 | M | 2/A | 13 | T | 99 | 58 | 14 | +12 |
Stage: defined according to Rai and Binet diagnostic criteria. YD: years since diagnosis. TX: therapy; NT: untreated.
*
Shown as percentage similarity to the closest germline gene.
-: missing data;
ND: none detected.