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Pathway Gene Description
Cell adhesion molecules (CAMs) HLA-DMB Major histocompatibility complex, class II, DM beta
ITGB7 Integrin, beta 7
ITGB1 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
HLA-DMA Major histocompatibility complex, class II, DM beta
SDC4 Syndecan 4 (amphiglycan, ryudocan)
HLA-DOB Homo sapiens major histocompatibility complex, class II, DO beta (HLA-DOB), mRNA.
SELP Selectin P (granule membrane protein 140kDa, antigen CD62)
NLGN1 Neuroligin 1
SELL Selectin L (lymphocyte adhesion molecule 1)
L1CAM L1 cell adhesion molecule
ICAM2 Intercellular adhesion molecule 2
ITGAM Integrin, alpha M (complement component 3 receptor 3 subunit)
ECM-receptor interaction ITGB7 Integrin, beta 7
ITGB1 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
SDC4 Syndecan 4 (amphiglycan, ryudocan)
Antigen processing and presentation HLA-DMB Major histocompatibility complex, class II, DM beta
HLA-DMA Major histocompatibility complex, class II, DM beta
HLA-DOB Homo sapiens major histocompatibility complex, class II, DO beta (HLA-DOB), mRNA.
Type I diabetes mellitus HLA-DMB Major histocompatibility complex, class II, DM beta
HLA-DMA Major histocompatibility complex, class II, DM beta
TNF Tumor necrosis factor (TNF superfamily, member 2)
HLA-DOB Homo sapiens major histocompatibility complex, class II, DO beta (HLA-DOB), mRNA.
Bile acid biosynthesis ACAD8 Acyl-Coenzyme A dehydrogenase family, member 8
LIPA Lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
ACAA1 Acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase)
Aminoacyl-tRNA biosynthesis QARS Glutaminyl-tRNA synthetase
HARSL Histidyl-tRNA synthetase-like
HARS Histidyl-tRNA synthetase
Histidine metabolism PRMT2 Protein arginine methyltransferase 2
HARS Histidyl-tRNA synthetase
HARSL Histidyl-tRNA synthetase-like
Epithelial cell signaling in Helicobacter pylori infection PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
IKBKB Golgi autoantigen, golgin subfamily a, 7
HBEGF Heparin-binding EGF-like growth factor
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
MAPK14 Mitogen-activated protein kinase 14
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis PIGA Phosphatidylinositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuria)
PIGK Phosphatidylinositol glycan anchor biosynthesis, class K
PIGG Phosphatidylinositol glycan anchor biosynthesis, class G
PIGL Phosphatidylinositol glycan anchor biosynthesis, class L
Alkaloid biosynthesis II MYST3 MYST histone acetyltransferase (monocytic leukemia) 3
MYST4 MYST histone acetyltransferase (monocytic leukemia) 4
LIPA Lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
1- and 2-Methylnaphthalene degradation MYST3 MYST histone acetyltransferase (monocytic leukemia) 3
MYST4 MYST histone acetyltransferase (monocytic leukemia) 4
ACAD8 Acyl-Coenzyme A dehydrogenase family, member 8
Benzoate degradation via CoA ligation MYST3 MYST histone acetyltransferase (monocytic leukemia) 3
ACAT1 Acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
MYST4 MYST histone acetyltransferase (monocytic leukemia) 4
HADHA Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
Limonene and pinene degradation MYST3 MYST histone acetyltransferase (monocytic leukemia) 3
HADHA Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
MYST4 MYST histone acetyltransferase (monocytic leukemia) 4
Glycerophospholipid metabolism MYST3 MYST histone acetyltransferase (monocytic leukemia) 3
GPAM Glycerol-3-phosphate acyltransferase, mitochondrial
MYST4 MYST histone acetyltransferase (monocytic leukemia) 4
LYPLA2 Lysophospholipase II
PPAP2C Phosphatidic acid phosphatase type 2C
Adherens junction ACTC1 Actin, alpha, cardiac muscle 1
CSNK2A2 Casein kinase 2, alpha prime polypeptide
ACTN3 Actinin, alpha 3
EP300 E1A binding protein p300
WASF2 CDNA clone IMAGE:3030163
MAP3K7 Mitogen-activated protein kinase kinase kinase 7
IQGAP1 IQ motif containing GTPase activating protein 1
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
SNAI2 Snail homolog 2 (Drosophila)
FGFR1 Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
SMAD3 SMAD family member 3
LMO7 LIM domain 7
TGFBR2 Transforming growth factor, beta receptor II (70/80kDa)
TGF-beta signaling pathway ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS6KB1 Ribosomal protein S6 kinase, 70kDa, polypeptide 1
EP300 E1A binding protein p300
BMPR1A Bone morphogenetic protein receptor, type IA
RPS6KB2 Ribosomal protein S6 kinase, 70kDa, polypeptide 2
TNF Tumor necrosis factor (TNF superfamily, member 2)
SMAD3 SMAD family member 3
TGFBR2 Transforming growth factor, beta receptor II (70/80kDa)
Ubiquitin mediated proteolysis ITCH Itchy homolog E3 ubiquitin protein ligase (mouse)
ANAPC7 Anaphase promoting complex subunit 7
EDD1 E3 ubiquitin protein ligase, HECT domain containing, 1
UBE2D2 Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
FZR1 Fizzy/cell division cycle 20 related 1 (Drosophila)
Tyrosine metabolism MYST3 MYST histone acetyltransferase (monocytic leukemia) 3
PRMT2 Protein arginine methyltransferase 2
MYST4 MYST histone acetyltransferase (monocytic leukemia) 4
Inositol phosphate metabolism PIK3C3 Phosphoinositide-3-kinase, class 3
MINPP1 Multiple inositol polyphosphate histidine phosphatase, 1
PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
PIP5K2B Phosphatidylinositol-4-phosphate 5-kinase, type II, beta
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
Phosphatidylinositol signaling system PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
CALM1 Calmodulin 1 (phosphorylase kinase, delta)
PIK3C3 Phosphoinositide-3-kinase, class 3
INPP5D Inositol polyphosphate-5-phosphatase, 145kDa
PRKCA Protein kinase C, alpha
PIP5K2B Phosphatidylinositol-4-phosphate 5-kinase, type II, beta
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
Oxidative phosphorylation NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
COX11 COX11 homolog, cytochrome c oxidase assembly protein (yeast)
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
COX8A Cytochrome c oxidase subunit 8A (ubiquitous)
Ribosome RPL39 Ribosomal protein L39
RPL21 Ribosomal protein L21
RPL22 Ribosomal protein L22
RPS26P10 Ribosomal protein S26 pseudogene 10
RPS26 Ribosomal protein S26
RPL15 Ribosomal protein L15
RPS23 Ribosomal protein S23
Arachidonic acid metabolism GGT1 Gamma-glutamyltransferase 1
LTC4S Leukotriene C4 synthase
ALOX5 Arachidonate 5-lipoxygenase
Glutathione metabolism GSTM2 Glutathione S-transferase M2 (muscle)
GSTM1 Glutathione S-transferase M1
GSTM4 Glutathione S-transferase M4
G6PD Glucose-6-phosphate dehydrogenase
GGT1 Gamma-glutamyltransferase 1
Metabolism of xenobiotics by cytochrome P450 GSTM4 Glutathione S-transferase M4
GSTM2 Glutathione S-transferase M2 (muscle)
GSTM1 Glutathione S-transferase M1
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
Cholera - Infection PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRKCA Protein kinase C, alpha
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
ARF3 ADP-ribosylation factor 3
Chondroitin sulfate biosynthesis CSGlcA-T chondroitin sulfate glucuronyltransferase
XYLT1 Xylosyltransferase I
ChGn chondroitin beta1,4 N-acetylgalactosaminyltransferase
Cytokine-cytokine receptor interaction TNF Tumor necrosis factor (TNF superfamily, member 2)
GH2 Chorionic somatomammotropin hormone 1 (placental lactogen)
IL1RAP Interleukin 1 receptor accessory protein
BMPR1A Bone morphogenetic protein receptor, type IA
TNFRSF1 7Tumor necrosis factor receptor superfamily, member 17
IL10RA Interleukin 10 receptor, alpha
HGF Human mRNA for hepatocyte growth factor (HGF).
TNFSF9 Tumor necrosis factor (ligand) superfamily, member 9
IL17RA Interleukin 17 receptor A
CXCL12 Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
TGFBR2 Transforming growth factor, beta receptor II (70/80kDa)
Glycan structures - biosynthesis 2 B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
STT3B STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
PIGA Phosphatidylinositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuria)
PIGK Phosphatidylinositol glycan anchor biosynthesis, class K
PIGG Phosphatidylinositol glycan anchor biosynthesis, class G
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
PIGL Phosphatidylinositol glycan anchor biosynthesis, class L
Fructose and mannose metabolism PFKL Phosphofructokinase, liver
GMPPA GDP-mannose pyrophosphorylase A
STT3B STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
SORD Sorbitol dehydrogenase
FUK Fucokinase
HK2 Hexokinase 2
Galactose metabolism PFKL Phosphofructokinase, liver
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
HK2 Hexokinase 2
Fatty acid metabolism ACAT1 Acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
ACOX1 Acyl-Coenzyme A oxidase 1, palmitoyl
ACAA1 Acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase)
HADHA Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
CYP4F8 Cytochrome P450, family 4, subfamily F, polypeptide 8
Glycan structures - biosynthesis 1 B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
ALG6 Asparagine-linked glycosylation 6 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
XYLT1 Xylosyltransferase I
EXT2 Exostoses (multiple) 2
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
RPN1 Ribophorin I
CSGlcA-T chondroitin sulfate glucuronyltransferase
ChGn chondroitin beta1,4 N-acetylgalactosaminyltransferase
EXTL2 Exostoses (multiple)-like 2
MAN1B1 Mannosidase, alpha, class 1B, member 1
MAN1A2 Mannosidase, alpha, class 1A, member 2
Huntington's disease DCTN1 Dynactin 1 (p150, glued homolog, Drosophila)
BAX BCL2-associated X protein
CALM1 Calmodulin 1 (phosphorylase kinase, delta)
EP300 E1A binding protein p300
Cell cycle BUB3 BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)
ANAPC7 Anaphase promoting complex subunit 7
EP300 E1A binding protein p300
YWHAE Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
ATR Ataxia telangiectasia and Rad3 related
SMAD3 SMAD family member 3
FZR1 Fizzy/cell division cycle 20 related 1 (Drosophila)
Valine, leucine and isoleucine degradation ACAT1 Acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
MYST3 MYST histone acetyltransferase (monocytic leukemia) 3
ACAA1 Acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase)
BCAT2 Branched chain aminotransferase 2, mitochondrial
MYST4 MYST histone acetyltransferase (monocytic leukemia) 4
HADHA Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
MUT Methylmalonyl Coenzyme A mutase
Amyotrophic lateral sclerosis (ALS) RAB5A RAB5A, member RAS oncogene family
BAX BCL2-associated X protein
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
CAT Catalase
SLC1A2 Homo sapiens solute carrier family 1 (glial high affinity glutamate transporter), member 2 (SLC1A2), mRNA.
Glycerolipid metabolism GPAM Glycerol-3-phosphate acyltransferase, mitochondrial
STT3B STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
PPAP2C Phosphatidic acid phosphatase type 2C
LIPA Lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
DNA polymerase POLD4 Polymerase (DNA-directed), delta 4
POLE4 Polymerase (DNA-directed), epsilon 4 (p12 subunit)
POLD3 Polymerase (DNA-directed), delta 3, accessory subunit
POLE3 Polymerase (DNA directed), epsilon 3 (p17 subunit)
POLE Polymerase (DNA directed), epsilon
Purine metabolism ADSS Adenylosuccinate synthase
PDE4C Phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)
XDH Xanthine dehydrogenase
POLR3H Polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POLR3K Polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
POLD4 Polymerase (DNA-directed), delta 4
POLE4 Polymerase (DNA-directed), epsilon 4 (p12 subunit)
DCK Deoxycytidine kinase
POLE3 Polymerase (DNA directed), epsilon 3 (p17 subunit)
POLD3 Polymerase (DNA-directed), delta 3, accessory subunit
GART Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
POLE Polymerase (DNA directed), epsilon
Pyrimidine metabolism POLR3H Polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POLD4 Polymerase (DNA-directed), delta 4
POLR3K Polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
DCK Deoxycytidine kinase
POLE4 Polymerase (DNA-directed), epsilon 4 (p12 subunit)
POLE3 Polymerase (DNA directed), epsilon 3 (p17 subunit)
DHODH Dihydroorotate dehydrogenase
POLD3 Polymerase (DNA-directed), delta 3, accessory subunit
TK2 Thymidine kinase 2, mitochondrial
POLE Polymerase (DNA directed), epsilon
Jak-STAT signaling pathway GH2 Chorionic somatomammotropin hormone 1 (placental lactogen)
AKT1 V-akt murine thymoma viral oncogene homolog 1
STAT6 Signal transducer and activator of transcription 6, interleukin-4 induced
CISH Cytokine inducible SH2-containing protein
EP300 E1A binding protein p300
PIAS4 Protein inhibitor of activated STAT, 4
PIAS3 Protein inhibitor of activated STAT, 3
IL10RA Interleukin 10 receptor, alpha
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b
STAT5B Signal transducer and activator of transcription 5B
Chronic myeloid leukemia AKT1 V-akt murine thymoma viral oncogene homolog 1
CTBP1 C-terminal binding protein 1
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
IKBKB Golgi autoantigen, golgin subfamily a, 7
GAB2 GRB2-associated binding protein 2
CTBP2 C-terminal binding protein 2
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SMAD3 SMAD family member 3
STAT5B Signal transducer and activator of transcription 5B
CRKL V-crk sarcoma virus CT10 oncogene homolog (avian)-like
TGFBR2 Transforming growth factor, beta receptor II (70/80kDa)
Adipocytokine signaling pathway AKT1 V-akt murine thymoma viral oncogene homolog 1
STK11 Serine/threonine kinase 11
TNF Tumor necrosis factor (TNF superfamily, member 2)
IKBKB Golgi autoantigen, golgin subfamily a, 7
PRKAB2 Protein kinase, AMP-activated, beta 2 non-catalytic subunit
IRS1 Insulin receptor substrate 1
SLC2A4 Solute carrier family 2 (facilitated glucose transporter), member 4
B cell receptor signaling pathway PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
AKT1 V-akt murine thymoma viral oncogene homolog 1
PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
CHP calcium binding protein P22
INPP5D Inositol polyphosphate-5-phosphatase, 145kDa
BLNK B-cell linker
IKBKB Golgi autoantigen, golgin subfamily a, 7
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Fc epsilon RI signaling pathway PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
AKT1 V-akt murine thymoma viral oncogene homolog 1
INPP5D Inositol polyphosphate-5-phosphatase, 145kDa
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
TNF Tumor necrosis factor (TNF superfamily, member 2)
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
GAB2 GRB2-associated binding protein 2
PRKCA Protein kinase C, alpha
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
MAPK14 Mitogen-activated protein kinase 14
Type II diabetes mellitus MAFA V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
TNF Tumor necrosis factor (TNF superfamily, member 2)
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
IRS1 Insulin receptor substrate 1
IKBKB Golgi autoantigen, golgin subfamily a, 7
SLC2A4 Solute carrier family 2 (facilitated glucose transporter), member 4
Focal adhesion PPP1CB Protein phosphatase 1, catalytic subunit, beta isoform
ACTN3 Actinin, alpha 3
AKT1 V-akt murine thymoma viral oncogene homolog 1
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
ITGB1 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
TLN1 Talin 1
ACTC1 Actin, alpha, cardiac muscle 1
PRKCA Protein kinase C, alpha
PPP1CA Protein phosphatase 1, catalytic subunit, alpha isoform
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
CAV2 Caveolin 2
ITGB7 Integrin, beta 7
HGF Human mRNA for hepatocyte growth factor (HGF).
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
GRLF1 Glucocorticoid receptor DNA binding factor 1
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
CRKL V-crk sarcoma virus CT10 oncogene homolog (avian)-like
Axon guidance PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
CHP calcium binding protein P22
ITGB1 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
NCK2 NCK adaptor protein 2
L1CAM L1 cell adhesion molecule
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
CXCL12 Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
Calcium signaling pathway ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
CALM1 Calmodulin 1 (phosphorylase kinase, delta)
PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
CHP calcium binding protein P22
CACNA1I Calcium channel, voltage-dependent, alpha 1I subunit
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
PRKCA Protein kinase C, alpha
SLC25A5 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
Pathogenic Escherichia coli infection - EHEC TUBB8 tubulin, beta 8
ACTC1 Actin, alpha, cardiac muscle 1
ITGB1 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
VIL2 Villin 2 (ezrin)
PRKCA Protein kinase C, alpha
NCK2 NCK adaptor protein 2
Long-term potentiation PPP1CB Protein phosphatase 1, catalytic subunit, beta isoform
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
CALM1 Calmodulin 1 (phosphorylase kinase, delta)
CHP calcium binding protein P22
PPP1CA Protein phosphatase 1, catalytic subunit, alpha isoform
EP300 E1A binding protein p300
PRKCA Protein kinase C, alpha
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
MAPK signaling pathway DUSP4 Dual specificity phosphatase 4
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
RASA2 RAS p21 protein activator 2
AKT1 V-akt murine thymoma viral oncogene homolog 1
FGF7 Fibroblast growth factor 7 (keratinocyte growth factor)
PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
MAX MYC associated factor X
CHP calcium binding protein P22
PPM1A Protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform
TNF Tumor necrosis factor (TNF superfamily, member 2)
MAP3K7 Mitogen-activated protein kinase kinase kinase 7
PRKCA Protein kinase C, alpha
CACNA1I Calcium channel, voltage-dependent, alpha 1I subunit
GNA12 Guanine nucleotide binding protein (G protein) alpha 12
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
IKBKB Golgi autoantigen, golgin subfamily a, 7
MAP3K4 Mitogen-activated protein kinase kinase kinase 4
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
FGFR1 Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
TRAF6 CDNA FLJ46539 fis, clone THYMU3037836
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
FGF2 Fibroblast growth factor 2 (basic)
MRAS Muscle RAS oncogene homolog
CRKL V-crk sarcoma virus CT10 oncogene homolog (avian)-like
TGFBR2 Transforming growth factor, beta receptor II (70/80kDa)
MAPK14 Mitogen-activated protein kinase 14
Apoptosis PRKAR1A Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
AKT1 V-akt murine thymoma viral oncogene homolog 1
BAX BCL2-associated X protein
MYD88 Myeloid differentiation primary response gene (88)
PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
IL1RAP Interleukin 1 receptor accessory protein
CHP calcium binding protein P22
TNF Tumor necrosis factor (TNF superfamily, member 2)
CASP9 Caspase 9, apoptosis-related cysteine peptidase
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
IKBKB Golgi autoantigen, golgin subfamily a, 7
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
Regulation of actin cytoskeleton PPP1CB Protein phosphatase 1, catalytic subunit, beta isoform
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
ACTC1 Actin, alpha, cardiac muscle 1
ARPC4 Actin related protein 2/3 complex, subunit 4, 20kDa
FGF7 Fibroblast growth factor 7 (keratinocyte growth factor)
PPP1CA Protein phosphatase 1, catalytic subunit, alpha isoform
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ACTN3 Actinin, alpha 3
ITGB1 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
VIL2 Villin 2 (ezrin)
WASF2 CDNA clone IMAGE:3030163
ITGB7 Integrin, beta 7
PIP5K2B Phosphatidylinositol-4-phosphate 5-kinase, type II, beta
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
GNA12 Guanine nucleotide binding protein (G protein) alpha 12
IQGAP1 IQ motif containing GTPase activating protein 1
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
CYFIP1 Cytoplasmic FMR1 interacting protein 1
FGFR1 Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
GRLF1 Glucocorticoid receptor DNA binding factor 1
FGF2 Fibroblast growth factor 2 (basic)
ITGAM Integrin, alpha M (complement component 3 receptor 3 subunit)
MRAS Muscle RAS oncogene homolog
CRKL V-crk sarcoma virus CT10 oncogene homolog (avian)-like
Insulin signaling pathway PPP1CB Protein phosphatase 1, catalytic subunit, beta isoform
PFKL Phosphofructokinase, liver
AKT1 V-akt murine thymoma viral oncogene homolog 1
PRKAR1A Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
RPS6KB1 Ribosomal protein S6 kinase, 70kDa, polypeptide 1
PPP1CA Protein phosphatase 1, catalytic subunit, alpha isoform
CALM1 Calmodulin 1 (phosphorylase kinase, delta)
RHOQ Ras homolog gene family, member Q
RPS6KB2 Ribosomal protein S6 kinase, 70kDa, polypeptide 2
FLOT1 Flotillin 1
INPP5D Inositol polyphosphate-5-phosphatase, 145kDa
IRS1 Insulin receptor substrate 1
IKBKB Golgi autoantigen, golgin subfamily a, 7
PRKAB2 Protein kinase, AMP-activated, beta 2 non-catalytic subunit
GYS1 Glycogen synthase 1 (muscle)
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b
PYGB Phosphorylase, glycogen; brain
SLC2A4 Solute carrier family 2 (facilitated glucose transporter), member 4
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
CRKL V-crk sarcoma virus CT10 oncogene homolog (avian)-like
Wnt signaling pathway CTBP1 C-terminal binding protein 1
WNT6 Wingless-type MMTV integration site family, member 6
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
CSNK2A2 Casein kinase 2, alpha prime polypeptide
PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
EP300 E1A binding protein p300
CHP calcium binding protein P22
MAP3K7 Mitogen-activated protein kinase kinase kinase 7
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
CTBP2 C-terminal binding protein 2
PSEN1 Presenilin 1 (Alzheimer disease 3)
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
TBL1X Transducin (beta)-like 1X-linked
PRKCA Protein kinase C, alpha
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
SMAD3 SMAD family member 3
DVL3 Dishevelled, dsh homolog 3 (Drosophila)
VEGF signaling pathway AKT1 V-akt murine thymoma viral oncogene homolog 1
PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
CHP calcium binding protein P22
PRKCA Protein kinase C, alpha
CASP9 Caspase 9, apoptosis-related cysteine peptidase
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
MAPK14 Mitogen-activated protein kinase 14
Melanogenesis CALM1 Calmodulin 1 (phosphorylase kinase, delta)
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
WNT6 Wingless-type MMTV integration site family, member 6
EP300 E1A binding protein p300
PRKCA Protein kinase C, alpha
DVL3 Dishevelled, dsh homolog 3 (Drosophila)
Notch signaling pathway CIR CBF1 interacting corepressor
CTBP1 C-terminal binding protein 1
PCAF P300/CBP-associated factor
EP300 E1A binding protein p300
PSEN1 Presenilin 1 (Alzheimer disease 3)
CTBP2 C-terminal binding protein 2
DVL3 Dishevelled, dsh homolog 3 (Drosophila)
Glioma PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
AKT1 V-akt murine thymoma viral oncogene homolog 1
PRKCA Protein kinase C, alpha
CALM1 Calmodulin 1 (phosphorylase kinase, delta)
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
Natural killer cell mediated cytotoxicity PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
CHP calcium binding protein P22
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
TNF Tumor necrosis factor (TNF superfamily, member 2)
PRKCA Protein kinase C, alpha
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
ICAM2 Intercellular adhesion molecule 2
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
T cell receptor signaling pathway PPP3R1 Protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)
CHP calcium binding protein P22
AKT1 V-akt murine thymoma viral oncogene homolog 1
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
TNF Tumor necrosis factor (TNF superfamily, member 2)
IKBKB Golgi autoantigen, golgin subfamily a, 7
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)
NCK2 NCK adaptor protein 2
Leukocyte transendothelial migration PLCG2 Phospholipase C, gamma 2 (phosphatidylinositol-specific)
ACTN3 Actinin, alpha 3
ACTC1 Actin, alpha, cardiac muscle 1
ITGB1 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
MMP2 Matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
VIL2 Villin 2 (ezrin)
PRKCA Protein kinase C, alpha
RASSF5 Ras association (RalGDS/AF-6) domain family 5
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
RHOH Ras homolog gene family, member H
GRLF1 Glucocorticoid receptor DNA binding factor 1
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
ITGAM Integrin, alpha M (complement component 3 receptor 3 subunit)
CXCL12 Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
MAPK14 Mitogen-activated protein kinase 14
Lysine degradation DLST Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
ACAT1 Acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
OGDH Oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
EHMT2 Euchromatic histone-lysine N-methyltransferase 2
EHMT1 Euchromatic histone-lysine N-methyltransferase 1
HADHA Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
Toll-like receptor signaling pathway AKT1 V-akt murine thymoma viral oncogene homolog 1
MYD88 Myeloid differentiation primary response gene (88)
TNF Tumor necrosis factor (TNF superfamily, member 2)
TRAF6 CDNA FLJ46539 fis, clone THYMU3037836
MAP3K7 Mitogen-activated protein kinase kinase kinase 7
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
IKBKB Golgi autoantigen, golgin subfamily a, 7
TLR2 Toll-like receptor 2
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
TICAM2 Toll-like receptor adaptor molecule 2
MAPK14 Mitogen-activated protein kinase 14
Long-term depression HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
GNAZ Guanine nucleotide binding protein (G protein), alpha z polypeptide
GNA12 Guanine nucleotide binding protein (G protein) alpha 12
PRKCA Protein kinase C, alpha
N-Glycan biosynthesis DHDDS Dehydrodolichyl diphosphate synthase
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
MAN1B1 Mannosidase, alpha, class 1B, member 1
ALG6 Asparagine-linked glycosylation 6 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)
MAN1A2 Mannosidase, alpha, class 1A, member 2
RPN1 Ribophorin I
DOLPP1 Dolichyl pyrophosphate phosphatase 1
Neuroactive ligand-receptor interaction GH2 Chorionic somatomammotropin hormone 1 (placental lactogen)
GPR156 G protein-coupled receptor 156
CRHR2 Corticotropin releasing hormone receptor 2
UTS2R Urotensin 2 receptor
PRLH Prolactin releasing hormone
LTB4R Leukotriene B4 receptor
Gap junction HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
TUBB8 tubulin, beta 8
PRKCA Protein kinase C, alpha
GnRH signaling pathway HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
MMP2 Matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
HBEGF Heparin-binding EGF-like growth factor
CALM1 Calmodulin 1 (phosphorylase kinase, delta)
PRKCA Protein kinase C, alpha
MAP3K4 Mitogen-activated protein kinase kinase kinase 4
MAPK14 Mitogen-activated protein kinase 14
Tight junction ACTN3 Actinin, alpha 3
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
PRKCA Protein kinase C, alpha
AKT1 V-akt murine thymoma viral oncogene homolog 1
CSNK2A2 Casein kinase 2, alpha prime polypeptide
ACTC1 Actin, alpha, cardiac muscle 1
MRAS Muscle RAS oncogene homolog
PRKCH Protein kinase C, eta
Tryptophan metabolism TRAF7 TNF receptor-associated factor 7
OGDH Oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
ACAT1 Acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
UHRF1 Ubiquitin-like, containing PHD and RING finger domains, 1
CYP4F8 Cytochrome P450, family 4, subfamily F, polypeptide 8
CAT Catalase
PRMT2 Protein arginine methyltransferase 2
HADHA Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
CNOT4 CCR4-NOT transcription complex, subunit 4
Colorectal cancer AKT1 V-akt murine thymoma viral oncogene homolog 1
BAX BCL2-associated X protein
CASP9 Caspase 9, apoptosis-related cysteine peptidase
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
SMAD3 SMAD family member 3
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
DVL3 Dishevelled, dsh homolog 3 (Drosophila)
TGFBR2 Transforming growth factor, beta receptor II (70/80kDa)
Pancreatic cancer AKT1 V-akt murine thymoma viral oncogene homolog 1
CASP9 Caspase 9, apoptosis-related cysteine peptidase
RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RALBP1 RalA binding protein 1
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
IKBKB Golgi autoantigen, golgin subfamily a, 7
SMAD3 SMAD family member 3
RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
TGFBR2 Transforming growth factor, beta receptor II (70/80kDa)
mTOR signaling pathway RICTOR rapamycin-insensitive companion of mTOR
AKT1 V-akt murine thymoma viral oncogene homolog 1
EIF4B Eukaryotic translation initiation factor 4B
RPS6KB2 Ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPS6KB1 Ribosomal protein S6 kinase, 70kDa, polypeptide 1
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
LYK5 protein kinase LYK5
STK11 Serine/threonine kinase 11
Melanoma FGF7 Fibroblast growth factor 7 (keratinocyte growth factor)
AKT1 V-akt murine thymoma viral oncogene homolog 1
HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
FGFR1 Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
HGF Human mRNA for hepatocyte growth factor (HGF).
FGF2 Fibroblast growth factor 2 (basic)
PIK3CD Phosphoinositide-3-kinase, catalytic, delta polypeptide
Neurodegenerative Disorders BAX BCL2-associated X protein
PRNP Prion protein (p27–30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
PSEN1 Presenilin 1 (Alzheimer disease 3)
EP300 E1A binding protein p300
GFAP Glial fibrillary acidic protein
Propanoate metabolism MUT Methylmalonyl Coenzyme A mutase
ACAT1 Acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
HADHA Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
Selenoamino acid metabolism SEPHS1 Selenophosphate synthetase 1
PRMT2 Protein arginine methyltransferase 2
GGT1 Gamma-glutamyltransferase 1
Thyroid cancer HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
CCDC6 Coiled-coil domain containing 6
TPM3 Tropomyosin 3
SNARE interactions in vesicular transport STX6 Syntaxin 6
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
STX16 Syntaxin 16
Starch and sucrose metabolism HK2 Hexokinase 2
PYGB Phosphorylase, glycogen; brain
AGL Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III)
GYS1 Glycogen synthase 1 (muscle)
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
Prion disease PRNP Prion protein (p27–30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
TNF Tumor necrosis factor (TNF superfamily, member 2)
GFAP Glial fibrillary acidic protein