Table 1. Demographics of patients used in the present study.
Values are means±S.D. or percentages (n).
| Demographic | Unmedicated patients with unipolar depression (n = 31) | Healthy comparison subjects (n = 31) | Between-group differences |
| Age (years) | 39.2±11.9 | 36.7±10.7 | F (1,60) = 0.73P = 0.40 |
| Female (n) | 77% (24) | 77% (24) | X2 = 0P = 1.0 |
| Right-handed (n) | 100% (31) | 94% (29) | X2 = 2.07P = 0.49 |
| Education level (years) | 15.4±3.4 | 15.3±2.7 | F (1,60) = 0.55P = 0.40 |
| Race | |||
| Caucasian (n) | 100% (31) | 93% (29) | X2 = 1.0P = 0.60 |
| African-American (n) | 0 | 7% (2) | – |
| Other (n) | 3% (1) | 0 | – |
| HDRS | 11.8±9.1 | – | – |
| Duration of illness (years) | 11.42±10.6 | – | – |
| Age at onset (years) | 27.9±11.6 | – | – |
| Number of episodes | 5.1±5.9 | – | – |
| Current mood state | – | – | |
| Depressed (n) | 65% (20) | – | – |
| Euthymic (n) | 35% (11) | – | – |
| Family history positive (n) | 65% (20) | – | – |
| Medication naïve (n) | 58% (18) | – | – |
| Previous atypical antipsychotic use (n) | 16% (5) | – | – |
| Previous antidepressant use (n) | 42% (13) | – | – |
| Hippocampal volume (mm3) | – | – | |
| Right | 1911.1±280.1 | 1828.9±284.2 | F (1,59) = 2.03P = 0.16 |
| Left | 1885.4±230.8 | 1851.9±326.8 | F (1,59) = 2.26P = 0.14 |