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. Author manuscript; available in PMC: 2010 Oct 1.

Published in final edited form as: Heart Fail Clin. 2009 Oct;5(4):501–514. doi: 10.1016/j.hfc.2009.04.002

Cardiac-related event risks associated with changes in BNP concentration (A) and NTproBNP concentrations (B) in ambulatory patients with heart failure. Hazard ratios (95% confidence interval) from Cox models relative to no changes in BNP or NTproBNP or no crossing over from more than to less than the BNP (500 ng/L) or NTproBNP (1000 ng/L) cutpoint values. Tx, transplantation. From Miller WL, Hartman KA, Grill DE, et al: Only large reductions in concentrations of natriuretic peptides (BNP and NT-proBNP) are associated with improved outcome in ambulatory patients with chronic heart failure. Clin Chem 2008(1):81, with permission.

Cardiac-related event risks associated with changes in BNP concentration (A) and NTproBNP concentrations (B) in ambulatory patients with heart failure. Hazard ratios (95% confidence interval) from Cox models relative to no changes in BNP or NTproBNP or no crossing over from more than to less than the BNP (500 ng/L) or NTproBNP (1000 ng/L) cutpoint values. Tx, transplantation. From Miller WL, Hartman KA, Grill DE, et al: Only large reductions in concentrations of natriuretic peptides (BNP and NT-proBNP) are associated with improved outcome in ambulatory patients with chronic heart failure. Clin Chem 2008(1):81, with permission.