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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Heart Fail Clin. 2009 Oct;5(4):501–514. doi: 10.1016/j.hfc.2009.04.002

Table 1.

Baseline parameters in studies evaluating NP guided therapy.

Study n Age
(years)		 NYHA class
(mean)		 NYHA class≥III
(%)		 LVEF
(%)		 Baseline NP
(pg/mL)		 Treatment goal
(pg/mL)
BNP
Murdoch 20 64/62 2.4/2.5 NA 25/25 139/111 pg/mL (mean) <50
STARS-BNP 220 66/65 2.2/2.3 21/29 32/30 NA/352 (mean) <100
NTproBNP
Troughton 69 68/72 2.3/2.3 28/33 28/26 1835/2122 <1700
TIME-CHF 499 77/76 NA 75/74 30/30 4657/3998 (median) <400 (60-74 years) <800 (≥75 years)
BATTLESCARRED 364 76-77 (median) ∼2.2 24 37 1997-2021 (median) <1300

Values are given for control group/hormone guided group or for groups combined. BATTLESCARRED consisted of three groups.