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. Author manuscript; available in PMC: 2009 Nov 30.
Published in final edited form as: J Mol Biol. 2006 Mar 9;358(4):1060–1070. doi: 10.1016/j.jmb.2006.02.049

Figure 2.

Figure 2

Cytoplasmic view of substrate binding and H+ translocation sites of LacY and homologs. Amino acid residues known (a), or predicted ((b)–(d)) to be involved in sugar binding (green) or H+ translocation (cyan) are shown as sticks. Essential residues are numbered according to protein sequences deposited in SwissProt Databank. (a) X-ray structure of LacY (PDB code 1PV7) with bound sugar β-d-galactopyranosyl-1-thio-β-d-galactopyranoside (TDG); (b) E. coli sucrose permease CscB; (c) E. coli raffinose permease RafB; (d) B. megaterium fructose permease FruP.