FIGURE 1.

A, a Venn diagram that showsthe homology overlap between the S. typhimurium model iMA945 and the E. coli model iAF1260. B, classification of the ORFs included in iMA945 grouped into COG functional categories. The length of each bar represents the number of genes in each COG that is included in the model. The percent assigned to each class refers to the coverage of the total number in the genome accounted for in the model. Some of the ORFs do not currently have a COG functional category assignment (here represented as N/A). Note that although each ORF is only counted once within each COG functional category, some ORFs have multiple COG category assignments.