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POSH stimulates the endocytosis of ROMK1. A, effect of POSH on potassium currents in oocytes injected with ROMK1 (R1)+POSH, R1+dominant negative dynamin (DynK44A) +POSH, and POSH+R1Δ373–378. B, effect of POSH on amiloride-sensitive sodium current in oocytes injected with ENaC (2 ng of α, 1 ng of β, and 1 ng of γ subunit).
