TABLE 1.

General characteristics of the ECT-deficient mice

The floxed mice had normal liver ECT activity, and the Pcyt2^−/− mice had an ECT-deficient liver. Values represent means ± S.D., n = 5. Assays were performed as described under “Experimental Procedures.”

	Males		Females
	Floxed	Pcyt2−/−	Floxed	Pcyt2−/−
Characteristic
Weight at 8 weeks, g	22.7 ± 2.0	22.6 ± 3.5	19.3 ± 2.3	18.0 ± 1.6
Weight at 12 weeks, g	27.3 ± 2.1	28.6 ± 4.4	22.4 ± 1.9	21.1 ± 0.9
Serum parameter
Triglycerides, mg/dl	146 ± 41	61 ± 5a	106 ± 15	81 ± 19a
Cholesterol, mg/dl	147 ± 12	148 ± 32	137 ± 9	114 ± 38
Albumin, g/dl	3.3 ± 0.2	3.5 ± 0.1	3.2 ± 0.1	3.4 ± 0.2
AST,b units/liter	342 ± 179	318 ± 118	225 ± 136	218 ± 110
ALT,c units/liter	78 ± 30	112 ± 41	65 ± 23	60 ± 12

^ap < 0.05.

^b AST means aspartate aminotransferase.

^c ALT means alanine aminotransferase.