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α-MSH inhibits melanoma cell migration through reduced expression of syndecan-2. B16 cells transfected with either the empty vector or sdc2 cDNA were treated with α-MSH (1.0 μm) for 24 h. Syndecan-2 expression levels (A) and cell migration (B) were analyzed as described in the legend to Fig. 3. Columns, average of three independent experiments. *, p < 0.01 versus control.
