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Amino acid preferences for pocket 1 (upper left panel), pocket 4 (upper right panel), pocket 6 (lower left panel), and pocket 9 (lower right panel) of the DR1401 motif. Black bars represent values within 2.5-fold of the reference peptide (RBA ≥ 0.4, “preferred”), hatched bars represent values within 10-fold of the reference peptide (RBA ≥ 0.1, “tolerated”), and open bars represent values less than 10-fold of the reference peptide (RBA ≤ 0.1, “excluded”).
