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Bright light preconditioning model. Mice were exposed to moderately bright cyclic light (600 lux; 12 h on/12 h off) for 6 days to induce endogenous protection in the retina. The mice were exposed to 3,000 lux light to induce LD and then to 50 lux cyclic light (12 h on/12 h off) for 4 days to recover. Photoreceptor function and morphology were subsequently assessed by electroretinography and histology.
