Table 3.

Macromolecules with fluorescent labels: Diffusion measured with IOI method

Molecule	Label	Mr	dH	D × 107	Species	Region	Prep.	°C	λ	Refs.
		× 103	nm	cm2s−1
Globular
AF-488	AF	0.547	1.1	44	turtle	cereb. ml	isolated	25	(1.44, 1.75)b	417
dex3	TMR/TR	3	2.7-3.2	19-23	rat	cortex	slice	34	1.74-1.81	crefs
dex3	TR	3	3.0	22	rat	cortex	in vivo	37	2.04,	391
dex3	TR	3	2.7	23	rat	hippo. CA1	slice	34	1.54,	145
dex3	TR	3	2.1	23	turtle	cereb. ml	isolated	25	(1.63, 2.05)b	417
dex10	TR	10	4.5	14	rat	cortex	slice	34	1.84	265, 379
dex40	TR	40	15	4.2	rat	cortex	slice	34	2.16	265
dex70	TR	70	16	3.8	rat	cortex	slice	34	2.25	265
dex70	TR	70	14	4.7	rat	cortex	in vivo	37	2.69	391
dex70	FITC	70	16	3.8	rat	striatum	slice	34	2.13	348
dex75	FITC	75	12	4.2	turtle	cereb. ml	isolated	25	(1.84, 2.45)b	417
dex282	FITC	282	21	2.3	turtle	cereb. ml	isolated	25	(2.21, 2.97)b	417
dex525	FITC	525	32	1.5	turtle	cereb. ml	isolated	25	(2.63, 3.49)b	417
Lactalbumin	TR	14.5	5.2	12	rat	cortex	slice	34	2.24	379
Ovalbumin	TR	45	6.1	10	rat	cortex	slice	34	2.50	379
BSA	TR	66	7.4	8.3	rat	cortex	slice	34	2.26	379
Lactoferrin	OG514	80	9.3	7.1	rat	cortex	in vivo	37	3.50	390
Transferrin	TR	80	8.8	7.5	rat	cortex	in vivo	37	2.29	390
EGF	OG514	6.6	3.7	17	rat	cortex	slice	34	1.79	388
β-NGFa	TMR	26.5	4.9	13	rat	striatum	slice	34	2.14	348
Flexible Chain
PHPMA	FITC	7.8		9.8	rat	cortex	slice	34	1.51	300
PHPMA	FITC	28		6.3	rat	cortex	slice	34	1.67	300
PHPMA	FITC/TR	47		4.7	rat	cortex	slice	34	1.55	300
PHPMA	FITC	220		2.0	rat	cortex	slice	34	1.65	300
PHPMA	FITC	515		1.2	rat	cortex	slice	34	1.58	300
PHPMA	FITC	1057		0.72	rat	cortex	slice	34	1.46	300
PHPMA-BSA	FITC	176		2.3	rat	cortex	slice	34	2.27	300
PEG	FITC	2		20	rat	cortex	slice	34	1.59	389
PEG	FITC	2		20	rat	striatum	slice	34	1.50	389
Nanoparticles
QD655	QD655	n/a	35	1.9	rat	cortex	in vivo	37	10.6	391

Footnotes

^amultiphoton techniques used in this study (see text)

^banisotropy measured in plane parallel to surface, (λ_x, λ_y)

^crefs = 145, 183, 265, 379, 375, 388

AF = AlexaFluor

FITC = Fluorescein isothiocyanate

TMR = Tetramethylrhodamine

OG515 = Oregon Green 515

TR = Texas Red

QD655 = Quantum Dot 655

hippo. CA1= hippocampus CA1 region. For other abbreviations see previous Tables.