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. Author manuscript; available in PMC: 2009 Nov 30.
Published in final edited form as: Physiol Rev. 2008 Oct;88(4):1277–1340. doi: 10.1152/physrev.00027.2007

Table 5.

Local intervention: Diffusion measured with RTI-TMA method

Intervention Region Species Age Prep. °C α Δα λ Δλ Refs.
stimulation
electrical spinal cord, dh rat adult in vivo 37-38 0.13-0.19 − 1.54 ~ 350
chemical injury spinal cord, dh rat adult in vivo 37-38 0.13-0.16 − 1.54 ~ 350
electrical spinal cord, dh frog adult isolated 17-19 0.13 − 1.60 ~ 299
electrical filum terminale frog adult isolated 17-19 0.28 − 1.60 + 299
K+, EAA
50 mM K+ spinal cord, dh rat P4-13 isolated 21-22 0.07-0.09 − 2.06-2.16 + 369
50 mM K+ spinal cord, dh rat P20-21 isolated 21-22 0.17 − 1.93 + 369
50 mM K+ spinal cord, wm rat P13-14 isolated 21-22 0.12 − 1.92,2.42 + 369
50 mM K+ spinal cord, dh mouse P8-10 slice 22 0.07 − 1.92 + 11
50 mM K+ spinal cord frog n/a isolated 17-19 0.09 − 1.70 + 299
50 mM K+ filum terminale frog n/a isolated 17-19 0.20 − 1.68 + 299
GLU 10−2 mM spinal cord rat P4-12 isolated 21-22 0.09 − 1.79 + 403
NMDA 10−4 mM spinal cord rat P4-12 isolated 21-22 0.09 − 1.83 + 403
AMPA 10−5 mM spinal cord rat P4-12 isolated 21-22 0.12 − 1.79 + 403
osmotic challengea
238 mosmol/kg cereb. grl turtle n/a isolated 21-23 0.12 − 1.79 + 178
461 mosmol/kg cereb. grl turtle n/a isolated 21-23 0.45 + 1.50 − 178
668 mosmol/kg cereb. grl turtle n/a isolated 21-23 0.6 + 1.50 − 178
150 mosmol/kg cortex rat adult slice 34 0.14 − 1.86 + 147
200 mosmol/kg cortex rat adult slice 34 0.12 − 1.82 + 183
400 mosmol/kg cortex rat adult slice 34 0.29 + 1.67 ~ 183
500 mosmol/kg cortex rat adult slice 34 0.42 + 1.68 ~ 183
215 mosmol/kg hippo. CA3 rat P5 slice 31 0.17 − 1.49 + 166
235 mosmol/kg spinal cord, dh rat P4-13 isolated 21-22 0.13-0.15 − 1.62-1.83 + 369
235 mosmol/kg spinal cord, dh rat P20-21 isolated 21-22 0.14 − 1.79 + 369
235 mosmol/kg spinal cord, wm rat P13-14 isolated 21-22 0.10 − 1.83, 2.00 + 369
200 mosmol/kg spinal cord rat P8-10 slice 22 0.15 − 1.62 + 401
400 mosmol/kg spinal cord rat P8-10 slice 22 0.30 + 1.54 ~ 401
200 mosmol/kg spinal cord, dh mouse P8-10 slice 22 0.12 − 1.63 + 11
175 mosmol/kg spinal cord frog n/a isolated 17-19 0.11 − 1.6 ~ 299
175 mosmol/kg filum terminale frog n/a isolated 17-19 0.22 − 1.39 ~ 299

Footnotes

Δα, Δλ Change in volume fraction or tortuosity relative to control values (see Table 4A, 4B)

+ = increase; − = decrease, ~ = no change

cereb. grl = cerebellum granule cell layer

a

normal osmolality ~ 300 mosmol/kg