Figure 4.

Inactivation of the recombinant and human PON1, and PON1-HDL complexes by hypochlorite. Recombinant and human PON1, and the corresponding HDL complexes, were incubated with increasing concentrations of hypochlorite at 37°C. Residual PON1 activity was determined after 24 hrs incubation, and plotted as percentage of the initial activity. Residual PON1 activity in the absence of hypochlorite remained largely unchanged for all the samples (≥ 75%). Data represents mean ± SD of 4 independent experiments.