Table 1.
Non-chimera | Chimera | p | |
---|---|---|---|
Cohort, n | 5 | 5 | |
Vital signs | |||
Body weight, g | 33.8±1.0 | 36.2±2.1 | 0.25 |
Body core temperature, °C | 35.2± 0.8 | 35.8±0.6 | 0.46 |
Respiration rate, /min | 117±3 | 112±2 | 0.34 |
Heart rate, beats/min | 469±10 | 455±9 | 0.29 |
Cardiovascular structure | |||
Ascending aorta, mm | 1.68±1.09 | 1.58±0.04 | 0.35 |
Main pulmonary artery, mm | 1.80±0.14 | 1.81±0.14 | 0.75 |
Right ventricular outflow tract, mm | 1.32±0.18 | 1.31±0.19 | 0.99 |
Left atrium, mm | 1.79±0.13 | 2.04±0.19 | 0.35 |
LVDd/BW, mm/g | 0.106±0.01 | 0.113±0.01 | 0.60 |
Left ventricular end-diastolic volume, μL | 59.2±3.3 | 61.5±6.3 | 0.92 |
Left wall thickness (septum plus posterior wall), mm | 1.43±0.05 | 1.56±0.08 | 0.25 |
Left ventricle/body weight, mg/g | 2.52±0.24 | 3.22±0.30 | 0.12 |
Cardiac function | |||
Fractional shortening, % | 46.6±2.8 | 45.4±3.1 | 0.75 |
Ejection fraction, % | 61.7±3.9 | 63.6±1.8 | 0.92 |
LVDd, left ventricular diastolic diameter. BW, body weight.