Table 1.
Clinic and laboratory data | Points for increasing abnormality1 | ||
---|---|---|---|
1 | 2 | 3 | |
HE (grade2) | None | SHE (0), 1-2 | 3-4 |
Ascites | None at US | Mild or controlled by diuretics | Present despite diuretics |
PT (% of activity)3 | > 70 | 70-40 | < 40 |
Albumin (g/dL) | > 3.5 | 2.8-3.5 | < 2.8 |
Bilirubin (mg/dL) | < 2 | 2-3 | > 3 |
1Scoring system: 5-6 points, grade A; 7-9 points, grade B; 10-15 points, grade C. 2HE: hepatic encephalopathy; Grade 0: sub-clinical hepatic encephalopathy, SHE, unravelled by Retain tests A or B; Grade 1: anxiety, irritability, depression, impaired concentration, sleep disturbances; Grade 2: disorientation, poor short-term memory, disinhibited behavior, drowsiness; Grade 3: somnolence, bizarre behavior, confusion, amnesia, paranoia; Grade 4: Coma. 3PT, Prothrombin Time, also expressed in seconds prolonged < 4; 4-6; > 6, or as INR < 1.7; 1.7-2.3; > 2.3. US: UltraSound.