Table 1.
Malaria patient data
| Patient no | Drug | Age (yrs) | Sex | Time to death (h) |
GCS Admission → Death |
Convulsions | CSF opening pressure (mmHg) | Additional Clinical History |
| CM1 | Q | 36 | F | 52 | 6 → 3 | No | High (20) | J, A, ARF, HG, S |
| CM2 | A | 22 | M | 38.5 | 7 → 3 | No | Normal (9.5) | J, HP, HG, S |
| CM3 | A | 69 | M | 336 | 8 → 3 | No | ND | J, A, ARF, HG, S |
| CM4 | Q | 34 | M | 6.6 | 8 → 3 | No | Normal (10) | J, A, ARF, PO, HG, S |
| CM5 | Q | 36 | M | 20.66 | 8 → 3 | Yes | High (23) | HP, J, ARF, HG, S |
| CM6 | Q | 30 | M | 36 | 7 → 3 | No | Normal (17) | J, A, ARF, PO, S |
| CM7 | Q | 29 | M | 9 | 6 → 3 | No | High (24) | PO, S |
| CM8 | Q | 63 | M | 16 | 10 → 3 | No | Normal (9) | A, HG, PO, S |
| CM9 | Q | 44 | M | 39 | 7 → 3 | No | High (21) | J, ARF, HG |
| CM10 | A | 44 | F | 24 | 7 → 3 | Yes | Normal (17) | A, S |
| NCM1 | Q | 22 | M | 6.33 | 14 → 3 | No | ND | J, HP, PO, S |
| NCM2 | Q | 63 | M | 50 | 11 → 3 | No | High (21.5) | J, A, ARF, PO, S |
| NCM3 | Q | 43 | F | 94.5 | 15 → 3 | No | ND | HP, J, A, ARF, HG, S |
| NCM4 | Q | 25 | M | 124 | 15 → 3 | No | ND | J, A, HG |
| NCM5 | Q | 22 | M | 6 | 11 → 3 | No | Normal (14) | HP, J, A, ARF, S |
| NCM6 | Q | 22 | F | 27.3 | 12 → 3 | No | ND | HP, J, ARF, HG, S |
| NCM7 | Q | 54 | M | 35 | 11 → 3 | Yes | Normal (13.5) | J, A, ARF, S |
| NCM8 | A | 56 | F | 4.66 | 13 → 3 | No | ND | J, ARF, S |
| NCM9 | Q | 24 | M | 113 | 14 → 3 | No | ND | J, A, S |
| NCM10 | A | 50 | F | 264 | 15 → 3 | No | High (19) | J, A, ARF, S |
Abbreviations: Q, quinine; A, artemether; CM, cerebral malaria; NCM, non-cerebral severe malaria; J, jaundice; A, anaemia; ARF, acute renal failure; HP, hyperparasitaemia; HG, hypoglycaemia, ND, not determined; S, haemodynamic shock, PO, pulmonary oedema.