Table 2.

International Prognostic Scoring System (IPSS)⁷

Factor	Value	IPSS score	Notes
Blasts	5% or less	0
	5% to 10%	0.5
	11% to 20%	1.5
	21% to 30%	2.0
Cytogenetics	= Good	0	Normal; -Y only; 5q- only; or 20q- only
	= Intermediate	0.5	Abnormalities other than good or poor
	= Poor	1.0	Complex; 3 or more abnormalities or abnormal chromosome 7
Cytopenias	0/1	0	Hemoglobin <10 g/dL; absolute neutrophil count (ANC) <1,500/μL; platelet count <100,000/μL; each count as a value of 1.
	2/3	0.5

Notes: The numeric scores for the blast %, the cytogenetic changes and the cytopenias are combined to give the total numeric score. The scores equal a risk category:

• Low.
• Intermediate-1.
• Intermediate-2.
• High.

The risk categories are sometimes combined as

• Low and intermediate-1 = low-risk MDS.
• Intermediate-2 and high = high-risk MDS.