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. Author manuscript; available in PMC: 2010 Jan 9.
Published in final edited form as: Cell Stem Cell. 2009 Jan 9;4(1):80–93. doi: 10.1016/j.stem.2008.11.011

Figure 4. Correlation between changes in histone modification and gene expression during differentiation from CD133+ to CD36+ cells.

Figure 4

The fold changes in both expression level and histone modification level were calculated for each gene during differentiation. The genes were grouped into 100-gene sets according to their expression changes and the changes were averaged for each set of 100 genes (one dot in the figure); the histone modification changes were then averaged for the same sets of 100-genes. The y-axis indicates the fold change (log10 scale) of histone modification in the promoter region (A) or gene body region (B). The x-axis indicates that the fold change in expression levels. The clear gaps in some figures are due to cut-off thresholds of histone modification islands.