Figure 6. Distinct histone modification changes are associated with different fates of the bivalent genes.
Histone modification profiles for the bivalent genes that lost H3K27me3 (A), H3K4me3 (B), both H3K27me3 and H3K4me3 (C), or remained as bivalent (D), during differentiation. H3K4me3, H3K27me3, H4K20me1, H2A.Z and Pol II profiles are shown here. The profiles for other modifications are shown in Figure S13.